Vyndaqel 2021 U.S. PROMOTIONAL AUDIT REPORT

Published July 2022 • 34 Pages

The 5 Key Questions Addressed by this Report:

• How many physicians were reached by Vyndaqel through reportable promotional activity in 2021 and how does this compare to its peer set in the HATTR Amyloidosis market?
• What promotional mix was leveraged (e.g., sales rep detailing, physician education, and paid speaking) and what was the median spend on each type of activity?
• How does Pfizer’s depth of coverage vary within key specialties (e.g., Cardiology, Nursing, Internal Medicine, Interventional Cardiology, Physician Assistant, Critical Care Medicine, Cardiac Electrophysiology, and Family Medicine) and how does this compare to its peers and the overall set of rep-accessible physicians?
• How often are physicians receiving paid meals for Vyndaqel throughout the year (e.g., monthly, quarterly, annually)?
• Who were the most frequent meal recipients and top paid speakers for Vyndaqel in 2021?

Data Sources and Methodology:

• MDDetails leverages company-reported financial transaction data disclosed through CMS Open Payments. This data set captures all transfers of value (e.g., speaking fees, consulting fees, travel, education, and meals) made on behalf of a drug or device manufacturer to a physician. Currently, over 5 years of longitudinal data is available – covering payments to more than 1,000,000 U.S. healthcare professionals.
• Over 31,110 paid interactions across 12,790 physicians made on behalf of Vyndaqel were carefully examined to support our analysis. In addition, interaction data from 2 peer products (e.g. Onpattro and Tegsedi ) was leveraged to provide benchmarking and market insights.