Ocrevus 2020 U.S. PROMOTIONAL AUDIT REPORT

Published July 2021 • 17 Pages

The 5 Key Questions Addressed by this Report:

• How many physicians were reached by Ocrevus through reportable promotional activity in 2020 and how does this compare to its peer set in the Multiple Sclerosis market?
• What promotional mix was leveraged (e.g., sales rep detailing, physician education, and paid speaking) and what was the median spend on each type of activity?
• How does Genentech’s depth of coverage vary within key specialties (e.g., Neurology) and how does this compare to its peers and the overall set of rep-accessible physicians?
• How often are physicians receiving paid meals for Ocrevus throughout the year (e.g., monthly, quarterly, annually)?
• Who were the most frequent meal recipients and top paid speakers for Ocrevus in 2020?

Data Sources and Methodology:

• MDDetails leverages company-reported financial transaction data disclosed through CMS Open Payments. This data set captures all transfers of value (e.g., speaking fees, consulting fees, travel, education, and meals) made on behalf of a drug or device manufacturer to a physician. Currently, over 5 years of longitudinal data is available – covering payments to more than 1,000,000 U.S. healthcare professionals.
• Over 3,800 paid interactions across 1,400 physicians made on behalf of Ocrevus were carefully examined to support our analysis. In addition, interaction data from 13 peer products (e.g. Aubagio, Avonex, Gilenya, Kesimpta, Lemtrada, Mavenclad, Mayzent, Plegridy, Rebif, Tecfidera, Tysabri, Vumerity, and Zeposia ) was leveraged to provide benchmarking and market insights.