Amitiza 2020 U.S. PROMOTIONAL AUDIT REPORT

Published July 2021 • 28 Pages

The 5 Key Questions Addressed by this Report:

• How many physicians were reached by Amitiza through reportable promotional activity in 2020 and how does this compare to its peer set in the Chronic Idiopathic Constipation, Irritable Bowel Syndrome, and Opioid-Induced Constipation markets?
• What promotional mix was leveraged (e.g., sales rep detailing, physician education, and paid speaking) and what was the median spend on each type of activity?
• How does Takeda’s depth of coverage vary within key specialties (e.g., Gastroenterology, Internal Medicine, Family Medicine, Anesthesiology, Pain Medicine, and Physical Medicine and Rehabilitation) and how does this compare to its peers and the overall set of rep-accessible physicians?
• How often are physicians receiving paid meals for Amitiza throughout the year (e.g., monthly, quarterly, annually)?
• Who were the most frequent meal recipients and top paid speakers for Amitiza in 2020?

Data Sources and Methodology:

• MDDetails leverages company-reported financial transaction data disclosed through CMS Open Payments. This data set captures all transfers of value (e.g., speaking fees, consulting fees, travel, education, and meals) made on behalf of a drug or device manufacturer to a physician. Currently, over 5 years of longitudinal data is available – covering payments to more than 1,000,000 U.S. healthcare professionals.
• Over 900 paid interactions across 700 physicians made on behalf of Amitiza were carefully examined to support our analysis. In addition, interaction data from 9 peer products (e.g. Kristalose, Linzess, Motegrity, Movantik, Relistor, Trulance, Viberzi, Xifaxan, and Zelnorm ) was leveraged to provide benchmarking and market insights.