Alprolix 2015 U.S. PROMOTIONAL AUDIT REPORT

Published July 2016 • 23 Pages

The 5 Key Questions Addressed by this Report:

• How many physicians were reached by Alprolix through personal promotion in 2015 and how does this compare to its peer set in the Hemophilia market?
• What promotional mix was leveraged (e.g., sales rep detailing, physician education, and paid speaking) and what was the median spend on each type of activity?
• How does Biogen’s depth of coverage vary within key specialties (e.g., Pediatric Medicine, Hematology/Oncology, and Hematology) and how does this compare to its peers and the overall set of rep-accessible physicians?
• How often are physicians receiving paid meals for Alprolix throughout the year (e.g., monthly, quarterly, annually)?
• Who were the most detailed prescribers and top paid speakers/consultants for Alprolix in 2015?

Data Sources and Methodology:

• MDDetails leverages company-reported financial transaction data disclosed through CMS Open Payments. This data set captures all transfers of value (e.g., speaking fees, consulting fees, travel, education, and meals) made on behalf of a drug or device manufacturer to a physician. Currently, 30 months of longitudinal data is available – covering payments to more than 800,000 U.S. healthcare professionals.
• Over 500 paid interactions across 200 physicians made on behalf of Alprolix were carefully examined to support our analysis. In addition, interaction data from 6 peer products (e.g. Advate, Eloctate, Kogenate, Novoeight, NovoSeven RT, and Xyntha Solofuse) was leveraged to provide benchmarking and market insights.