Adynovate 2019 U.S. PROMOTIONAL AUDIT REPORT

Published July 2020 • 22 Pages

The 5 Key Questions Addressed by this Report:

• How many physicians were reached by Adynovate through reportable promotional activity in 2019 and how does this compare to its peer set in the Hemophilia market?
• What promotional mix was leveraged (e.g., sales rep detailing, physician education, and paid speaking) and what was the median spend on each type of activity?
• How does Shire’s depth of coverage vary within key specialties (e.g., Pediatric Medicine, Internal Medicine, and Hematology/Oncology) and how does this compare to its peers and the overall set of rep-accessible physicians?
• How often are physicians receiving paid meals for Adynovate throughout the year (e.g., monthly, quarterly, annually)?
• Who were the most frequent meal recipients and top paid speakers for Adynovate in 2019?

Data Sources and Methodology:

• MDDetails leverages company-reported financial transaction data disclosed through CMS Open Payments. This data set captures all transfers of value (e.g., speaking fees, consulting fees, travel, education, and meals) made on behalf of a drug or device manufacturer to a physician. Currently, over 5 years of longitudinal data is available – covering payments to more than 1,000,000 U.S. healthcare professionals.
• Over 200 paid interactions across 100 physicians made on behalf of Adynovate were carefully examined to support our analysis. In addition, interaction data from 17 peer products (e.g. Advate, Afstyla, Alphanate, Alprolix, BeneFix, Eloctate, Hemlibra, Idelvion, Jivi, Kogenate, Kovaltry, Novoeight, NovoSeven RT, Nuwiq, Obizur, Rebinyn, and Xyntha Solofuse ) was leveraged to provide benchmarking and market insights.