Advate 2018 U.S. PROMOTIONAL AUDIT REPORT

Published July 2019 • 24 Pages

The 5 Key Questions Addressed by this Report:

• How many physicians were reached by Advate through reportable promotional activity in 2018 and how does this compare to its peer set in the Hemophilia market?
• What promotional mix was leveraged (e.g., sales rep detailing, physician education, and paid speaking) and what was the median spend on each type of activity?
• How does Shire’s depth of coverage vary within key specialties (e.g., Pediatric Medicine, Hematology/Oncology, Internal Medicine, and Dentistry) and how does this compare to its peers and the overall set of rep-accessible physicians?
• How often are physicians receiving paid meals for Advate throughout the year (e.g., monthly, quarterly, annually)?
• Who were the most frequent meal recipients and top paid speakers for Advate in 2018?

Data Sources and Methodology:

• MDDetails leverages company-reported financial transaction data disclosed through CMS Open Payments. This data set captures all transfers of value (e.g., speaking fees, consulting fees, travel, education, and meals) made on behalf of a drug or device manufacturer to a physician. Currently, over 5 years of longitudinal data is available – covering payments to more than 1,000,000 U.S. healthcare professionals.
• Over 300 paid interactions across 100 physicians made on behalf of Advate were carefully examined to support our analysis. In addition, interaction data from 12 peer products (e.g. Adynovate, Afstyla, Alphanate, Alprolix, Eloctate, Hemlibra, Kogenate, Kovaltry, Novoeight, NovoSeven RT, Obizur, and Xyntha Solofuse ) was leveraged to provide benchmarking and market insights.