Strensiq 2021 U.S. PROMOTIONAL AUDIT REPORT

Published July 2022 • 28 Pages

The 5 Key Questions Addressed by this Report:

• How many physicians were reached by Strensiq through reportable promotional activity in 2021 to drive use within the Hypophosphatasia market?
• What promotional mix was leveraged (e.g., sales rep detailing, physician education, and paid speaking) and what was the median spend on each type of activity?
• How does Alexion’s depth of coverage vary within key specialties (e.g., Nursing, Endocrinology, Rheumatology, Physician Assistant, Family Medicine, Internal Medicine, and Pediatric Medicine) and how does this compare to the overall set of rep-accessible physicians?
• How often are physicians receiving paid meals for Strensiq throughout the year (e.g., monthly, quarterly, annually)?
• Who were the most frequent meal recipients and top paid speakers for Strensiq in 2021?

Data Sources and Methodology:

• MDDetails leverages company-reported financial transaction data disclosed through CMS Open Payments. This data set captures all transfers of value (e.g., speaking fees, consulting fees, travel, education, and meals) made on behalf of a drug or device manufacturer to a physician. Currently, over 5 years of longitudinal data is available – covering payments to more than 1,000,000 U.S. healthcare professionals.
• Over 3,760 paid interactions across 2,380 physicians made on behalf of Strensiq were carefully examined to support our analysis.